Consequences of explosive population growth on tracts of Identity-by-Descent

Andrew Clark
Cornell University

The human population has expanded roughly 1000-fold in the last 100 generations, and this fantastic growth may distort many of the fundamental principles of population genetics. The distribution of lengths of IBD blocks in the genome is influenced by many factors, including local recombination rate, effective population size, distribution of family size, and population demography. Here we investigate by mathematics and by computer simulation the impact of exceptionally rapid population expansion on IBD tract lengths. Results will be compared to the results from IBD inferences from Illumina SNP array data.

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