|
|
|
Cells and Materials: At the Interface between Mathematics, Biology and EngineeringWorkshop IV: Systems Biology and Molecular ModelingMay 22 - 26, 2006Organizing Committee:
James Glazier
(Indiana University, Biocomplexity Institute)
Scientific BackgroundSystems biology involves the quantitative and simultaneous integration of different and multiple biological components and their relationships with one another. For example, the components may be proteins, while their relationships may be described by signal transduction pathways. Unlike systems biology, molecular modeling focuses on a single complex between biomolecules and computes the interactions that exist in the complex. Although the two fields appear dissimilar, they are both quantitative in nature and involve many components and relationships. In the case of molecular modeling, the components are the atoms and their partial charges, and their relationships are the different interactions between them. Therefore, it’s no surprise that some molecular modeling methods are now being applied to systems biology. Moreover, there has been recent success in combining these two fields to rationally design effective therapeutics. In this program, we will bring together experts in these two fields of computational biology to discuss their frontier research. Mathematical approaches: Differential equations, finite difference methods, Bayesian approaches, molecular dynamics, stochastic systems, clustering, nonlinear dynamics, Monte Carlo simulations, simulated annealing.< SpeakersChristoph Adami (Keck Graduate Institute)Reka Albert (Pennsylvania State University) Joel Bader (Johns Hopkins University) Ivet Bahar (University of Pittsburgh) Gaudenz Danuser (The Scripps Research Institute) Richard Dickinson (University of Florida) Drew Endy (Massachusetts Institute of Technology) Raymond Goldstein (University of Arizona) Steven Gross (University of California, Irvine) Armin Kaiser (Stanford University) Daniel Kamei (UCLA) Kevin Karplus (UC Santa Cruz) Arthur Lander (University of California, Irvine) Jim McGrath (University of Rochester) Hans Meinhardt (Max-Planck-Institut für Entwicklungsbiologie (Developmental Biology)) Shayn Peirce-Cottler (University of Virginia) Christopher Rao (University of Illinois at Urbana-Champaign) Michael Samoilov (Howard Hughes Medical Institute) William Smith (UC Santa Barbara) David Stocum (Indiana University - Purdue University) Sean Sun (Johns Hopkins University) Claire Tomlin (Stanford University) Denise Wolf (Lawrence Berkeley Laboratory) Contact Us:Institute for Pure and Applied Mathematics (IPAM) |
|
|