Abstract - IPAM

Abstract

Surface-based approaches to spatial localization and registration in primate cerebral cortex

David van Essen

Washington University/School of Medicine

Explicit surface reconstructions provide invaluable substrates for visualizing and analyzing the complex convolutions of the cerebral cortex. This report illustrates the utility of surface-based atlases of the human and macaque monkey brain for representing various aspects of cortical organization and function. These include multiple cortical partitioning schemes, as well as an open-ended collection of complex activation patterns derived from fMRI studies.

Surface-based registration from one hemisphere to another offers a powerful framework for (i) objectively and quantitatively representing both the consistencies and variability in cortical folding patterns and functional activation maps associated with specific tasks, and (ii) enabling cross-species comparisons and evaluating candidate homologies between cortical areas or functionally defined regions.
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