Probabilistic analysis of rates of gene duplication and transfers among Mollicutes and Cyanobacteria

Jens Lagergren
Royal Institute of Technology (KTH)

Incongruences between gene trees and corresponding species trees are common. Gene duplication, gene loss, and lateral gene transfer are three types of evolutionary events that can cause such incongruences. I will first describe our probabilistic model of nucleotide substitutions, gene duplication, gene loss, and lateral gene transfer. This model requires a dated species tree and can be used to reconstruct a gene tree for a gene family of interest and simultaneously reconcile the gene tree with the species tree. I will then describe how we used our MCMC framework PrIME, based on the model, to analyze gene families from Mollicutes and Cyanobacteria as well as the results obtained.

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