Workshop IV: Molecular Machines - IPAM

Workshop IV: Molecular Machines

Part of the Long Program Proteomics: Sequence, Structure, Function
May 24 - 28, 2004

Schedule

All times in this Schedule are Pacific Time (PT)

Monday, May 24, 2004

Morning Session

08:30-09:20
Check-In/Light Breakfast (Hosted by IPAM)
09:20-09:30
Welcome and Opening Remarks
09:30-10:30
David Bensimon (Ecole Normale Supérieure, France)
DNA/protein interactions at the single molecule level
10:30-11:00
Break
11:00-12:00
Sunney Xie (Harvard University)
Single Molecule Enzymology: From In vitro to In vivo Studies

Afternoon Session

12:00-14:00
Lunch (on your own)
14:00-15:00
Yi-der Chen (National Institute of Health)
Chemical-Mechano Free-Energy Transduction: From Muscles to Protein Motors and Brownian Ratchets
15:00-16:00
Michelle Wang (Cornell University)
Sequence-Dependent Kinetic Model for Transcription Elongation by RNA Polymerase
16:00-16:30
Break
16:30-17:30
Saveez Saffarian (Washington University/School of Medicine)
Interstitial Collagenase is an ATP-independent Molecular Motor Driven by Proteolysis of Collagen
17:30-19:00
Wine Reception (Hosted by IPAM)
19:00-20:00
George Oster (University of California, Berkeley (UC Berkeley))
Rotary Protein Motors

Tuesday, May 25, 2004

Morning Session

08:30-09:30
Continental Breakfast
09:30-10:30
Tom Chou (University of California, Los Angeles (UCLA))
Clustered bottlenecks in mRNA translation and protein synthesis
10:30-11:00
Break
11:00-12:00
Jacques Prost (Institut Curie, France)
Title not available

Afternoon Session

12:00-14:00
Lunch (on your own)
14:00-15:00
Edward Pate (Washington State University)
Conformational Changes at the Nucleotide-Binding Site of Kinesin-Family Motors
15:00-16:00
Qiang Cui (University of Wisconsin)
Preliminary insights into mechanochemical couplings in myosin with molecular simulations
16:00-16:30
Break
16:30-17:30
Brian Walton (University of Washington)
Hidden Markov model analysis of motor protein data

Wednesday, May 26, 2004

Morning Session

08:30-09:30
Continental Breakfast
09:30-10:30
Matthias Rief (University of Munich)
Single Molecule Mechanics of Proteins – Forces and Energy Landscapes
10:30-11:00
Break
11:00-12:00
Frank Julicher (Max Planck Institute)
Cellular oscillations powered by motor proteins

Afternoon Session

12:00-14:00
Lunch (on your own)
14:00-15:00
Ron Fox (Georgia Institute of Technology)
Rectified Brownian Motion in Subcellular Biology
15:00-16:00
Dean Astumian (Maine)
Physics of Brownian Motors and Pumps: Swimming in Molasses and Walking in a Hurricane
16:00-16:30
Break
16:30-17:30
Giovanni Cappello (Institut Curie, France)
Kinesin step without external force takes less than 70 microseconds

Thursday, May 27, 2004

Morning Session

08:30-09:30
Continental Breakfast
09:30-10:30
Anatoly Kolomeisky (Rice University)
Understanding Mechanochemical Coupling in Kinesins Using First-Passage Times
10:30-11:00
Break
11:00-12:00
Christian Maes (University of Leuven)
Recent results in nonequilibrium statistical mechanics

Afternoon Session

12:00-14:00
Lunch (Hosted by IPAM)
14:00-15:00
Scot Kuo (Johns Hopkins University)
Actin-based motility of Listeria monocytogenes
15:00-16:00
Reinhard Lipowsky (Max Planck Institute)
Stochastic Movements of Molecular Motors
16:00-16:30
Break
16:30-17:30
Meredith Betterton (University of Colorado)
Interaction of motor proteins with obstacles: Helicase unwinding of DNA

Friday, May 28, 2004

Morning Session

08:30-09:30
Continental Breakfast
09:30-10:30
Josh Baker (University of Vermont)
Talking heads: Myosin motors and the mechanical signals they send and receive
10:30-11:00
Break
11:00-12:00
Michael Sheetz (Columbia University)
Modeling of Cell Spreading Through Phases and Cytoskeletal Transport of Signals

Afternoon Session

12:00-13:30
Lunch (on your own)
13:30-14:30
Jerome Percus (New York University)
A Format for Molecular Motor Analysis
14:30-15:30
Ronald Rock (University of Chicago)
The Large Step Size of Myosin VI Requires Flexibility in the Proximal Tail Region
15:30
Conclusion
15:30-15:30
David Colquhoun (University College London)
Single ion channels: theory and practice of the analysis of a single molecule
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